Saturday, May 25, 2024
Nature's Pharmacy

7 Health Benefits of Berberine (Berberine hydrochloride)

Berberine (Berberine hydrochloride), is an extract of plants, notably the Berberis genus of shrubs. Berberine is a bioactive chemical. In the scientific community, it is categorized as an alkaloid. It is frequently used as a dye and has a yellow tint.

The drug has been a staple of ayurvedic therapy for millennia. This has a variety of effects on the body and has the power to alter the cells in different ways.

Diabetes, obesity, and heart issues are just a few of the metabolic health concerns that berberine is effective in treating.

Berberine or berberine hydrochloride originates from China and India, where it was initially used in Traditional Chinese Therapy and Ayurvedic medicine thousands of years ago.

What purpose does berberine serve today? Numerous pharmacological actions, such as antibacterial, anticancer, anti-inflammatory, and blood glucose-lowering properties, have been demonstrated in investigations.

In general, berberine HCL and other extracts and supplements derived from it are affordable, secure, and well-known for their extensive antibacterial properties. Even without the use of antibiotics, they could be able to aid in the natural treatment of illnesses.

Read Also: Berberine – Importance and Health Benefits

7 Health Benefits of Berberine (berberine hydrochloride)

7 Health Benefits of Berberine (Berberine hydrochloride)
Berberine (berberine hydrochloride)

1. Treatment For Diabetes

In one investigation, berberine (berberine hydrochloride) was discovered to assist in lowering blood sugar.

This can aid in the prevention and treatment of type II diabetes, as well as associated side effects such as diabetic neuropathy and cardiovascular disease.

Additionally, it has been demonstrated to benefit patients with metabolic syndrome in terms of insulin resistance, inflammatory markers, and glucose-lipid metabolism.

One of the most impressive trials compared the popular diabetes medication metformin versus taking 500 milligrams of the chemical two to three times each day for three months.

Researchers referred to berberine as a “potent oral hypoglycemic agent” since it was able to regulate blood sugar and lipid metabolism just as well as metformin.

Additional research has revealed that berberine corrects issues with lipid metabolism and glucose absorption.

For instance, berberine has been shown in a study published in Evidence-Based Complementary and Alternative Medicine to enhance insulin sensitivity via regulating adipokine secretion.

Some studies suggest that this substance may help avoid kidney damage by improving insulin sensitivity.

2. Lower High-Level Cholesterol And High Blood Pressure

There is proof that berberine may aid in lowering high levels of LDL, total cholesterol, and blood pressure.

According to research in the journal Metabolism, type 2 diabetes patients who took berberine had lower triglyceride and blood cholesterol levels. According to Harvard Medical School studies, it appears to function by blocking PCSK9, which lowers cholesterol.

According to a different study, taking red yeast rice and berberine together may offer a broader range of cholesterol protection with a lower risk of serious side effects than taking prescription statin therapy. Red yeast rice is well known for its ability to naturally lower cholesterol.

Berberine is also known as berberine hydrochloride has been demonstrated in animal tests to reduce unusually high levels of lipids and fats in the blood by encouraging hepatic cholesterol excretion and preventing intestine cholesterol absorption.

It assists women with polycystic ovarian syndrome (PCOS) as well since it can lower blood sugar, enhance LDL cholesterol and triglyceride levels, decrease testosterone levels, and lower waist-to-hip ratio.

When combined with a nutritious diet rich in antioxidants or supplements like folic acid, coenzyme Q10, and astaxanthin, it can also lower blood pressure and improve circulation in persons with metabolic syndrome.

Read Also: Barberry (Berberis vulgaris): Importance and Health Benefits

3. For Weight Loss

One of the few substances, berberine, can activate adenosine monophosphate-activated protein kinase (or AMPK). The enzyme AMPK, which is found inside human body cells, is frequently referred to as a “metabolic master switch” since it is so important in controlling metabolism.

Studies have shown that berberine may help prevent fat buildup in the human body and safeguard against metabolic syndrome because AMPK activation increases fat burning in the mitochondria.

This study showed that berberine is a powerful lipid-lowering substance with a mild weight loss impact.

4. Supports Heart Health

Berberine’s potential to reduce blood sugar levels and obesity, two factors that can increase the risk of coronary heart disease, may contribute to the compound’s beneficial effects on heart health.

Additionally, it promotes the production of nitric oxide, a signaling molecule that relaxes the arteries, boosts blood flow, reduces blood pressure, and guards against arteriosclerosis.

According to a study in the World Journal of Cardiology, those who took berberine had better heart health and could exercise more effectively than those who took a placebo.

Berberine’s cardiovascular side effects also point to a potential medicinal role for it in the management of arrhythmias and heart failure.

5. Improves Lungs Health

Due to its anti-inflammatory properties, research suggests that berberine improves lung function. Even the acute lung inflammation brought on by smoking can be lessened by this alkaloid.

One study that appeared in the journal Inflammation involved giving mice 50 mg/kg of berberine intragastrically after exposing them to cigarette smoke to create acute lung damage.

Examining lung tissues revealed that smoking led to cellular edema, or abnormal fluid retention, as well as inflammation of the lung’s alveoli.

However, berberine’s anti-inflammatory activity allowed for pretreatment, which greatly reduced lung inflammation and improved acute lung injury brought on by cigarette smoke.

6. Protects The Liver

How does berberine affect the liver? Early research reveals that berberine helps the liver by reducing blood sugar, insulin resistance, and triglycerides, which are indicators of liver damage in patients with diabetes and viruses like hepatitis; additional studies are required to confirm it can protect against liver illnesses.

It might also be able to help those who suffer from fatty liver disease. Berberine has been shown to have anti-hyperglycemic and anti-dyslipidemic actions, which means that it enhances glucolipid metabolism and can help treat the underlying reasons for fatty liver disease.

7. Anti-cancer

The modulation of cancer cell metabolism by berberine hydrochloride is a topic of growing interest. This is because berberine may aid in the killing of cancer cells.

It is anticipated to become a natural component of the nanoparticulate delivery methods used for cancer berberine therapy due to its anticancer effect, specifically limiting the growth and proliferation of cancer cells.

For instance, a study carried out at China Medical University discovered that berberine triggered apoptosis in human tongue cancer cells.

Read Also: Basil (Ocimum Basilicum) – Importance and Health Benefits

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Benadine Nonye is an agricultural consultant and a writer with over 12 years of professional experience in the agriculture industry. - National Diploma in Agricultural Technology - Bachelor's Degree in Agricultural Science - Master's Degree in Science Education - PhD Student in Agricultural Economics and Environmental Policy... Visit My Websites On: 1. - Your Comprehensive Practical Agricultural Knowledge and Farmer’s Guide Website! 2. - For Effective Environmental Management through Proper Waste Management and Recycling Practices! Join Me On: Twitter: @benadinenonye - Instagram: benadinenonye - LinkedIn: benadinenonye - YouTube: Agric4Profits TV and WealthInWastes TV - Pinterest: BenadineNonye4u - Facebook: BenadineNonye

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